Erythropoietin and the Nervous System

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Erythropoietin in the central nervous system, and its use to prevent hypoxic-ischemic brain damage.

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Amazon Inspire Digital Educational Resources. Amazon Rapids Fun stories for kids on the go. Collectively, the evidence suggests that Epo may provide a new approach to the treatment of a variety of CNS disorders in adults and children, especially as a possible therapy for perinatal asphyxia. This review summarizes the current knowledge on the neurotrophic and neuroprotective functions of Epo in the developing and injured brain.

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Erythropoietin and the nervous system - ScienceDirect

Didn't get the message? Erythropoietin Epo is a hematopoietic growth factor and cytokine which stimulates erythropoiesis. In recent years, Epo has been shown to have important nonhematopoietic functions in the nervous system. Nonerythropoietic actions of Epo include a critical role in the development, maintenance, protection and repair of the nervous system. A wide variety of experimental studies have shown that Epo and its receptor are expressed in the nervous system and Epo exerts remarkable neuroprotection in cell culture and animal models of nervous system disorders.